COVID-19: A Review in COVID-19 Infections and Treatment through Understanding Viral First Main Steps in Respiratory Cells
Journal: International Journal of Science and Research (IJSR) (Vol.9, No. 8)Publication Date: 2020-08-05
Authors : Ashraf Marzouk El Tantawi;
Page : 1154-1158
Keywords : ribosomal transferase; G-actin ATPase methylation; tropomyosin; rapamycin; Remdesivir; ATP drug; CoA phospho_acetyltransferase; COVID-19;
Abstract
COVID-19 pandemic, induces a viral protein called open reading frame 3b (ORF3b) actively blocks the induction of type I interferon which are polypeptides that are secreted by infected cells. Antiviral defense called interferon that produced by sick cells originally from ribosomal functions, which plays a really important role in slowing virus infection. Interferon is considered to be the initiative primary messages started from ribosome in the infected cells to follow the right original biological pathways to reach brain for asking for protection, recoveries and facing the viral infection. When Corona virus started to infect human body started by respiratory system, that to minimize the intake oxygen to infected body, that when viral effects reach the blood stream in arteries& in capillaries wil affects on red blood cells to lysis& break their main -ve linkages which original presence in ATP molecules to restore their O2, phosphate gps,& their attached biological peptides that will bind& connected to viral protein to follow viral metabolism and viral toxic productions. Then the result will be reduction in gas exchanges in lungs that the intake oxygen will be minimized, and the restored CO2 in tissues& capillaries will be increased, that will leads to increase toxicities in capillaries then in arteries. When virus starts to infect respiratory cells, first will lysis and destroy actin filaments and their isoform including their ATPase which considered being a part of G-actin filaments. So, first Symptom is the Symptoms is the loss of sensations delivers by G-actin and tropomyosin isoforms, then loss of tast of smells which is done& transfered by G-actin and tRNAs directly to brain and then to neuron cells to give their responds& answers to those received messages of sensations and tastes.
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