A Comparative Clinical Trail to Evaluate the Efficacy of Indukanta Ghrita Matra Basti and Mustakarishta with Changeri Ghrita Matra Basti and Maha Kalyanaka Kashaya in the Management of Grahani Roga vis-a-vis Irritable Bowel Syndrome (IBS)

Grahani roga is the main disease of gastrointestinal tract. Conditions like Muhurbaddha muhurdrava malapravrutti, ( irregular bowel habits) Ama mala privrutti (stool with mucus) UdaraShoola (abdominal pain), Ajeerna (indigestion), Aruchi (anorexia), Adhmana (distention of abdomen), have been described under the heading of Grahani Roga. Which analogues with Irritable bowel syndrome of contemporary medicinewhich is a chronic, relapsing functional disorder characterized by abdominal pain, bloating& amp; changes in bowel habit. Present study is to evaluate and compare the efficacy of Indukanta ghrita matra basti and Mustakarishta with Changeri ghrita matra basti and Maha kalyanaka kashaya in the management of Grahani roga vis-à-vis Irritable bowel syndrome. The clinical study with a pre-post test design included 42 subjects between the age group of 18-60 years. The results obtained after the completion of intervention showed statistically significant with ‘p’ value less than 0.001 and also overall assessment showed marked (75 %) improvement in all 42 subjects. Grahani roga being Agni dushti and Pittadhara kaladushti janyavyadhi drugs which are deepana, pachana, vathanulomaka and grahi pacified the signs and symptoms of Grahani roga vis-à-vis IBS