Prospective Analysis of Outcome in Patients with Peptic Ulcer Perforation in Tertiary Care Hospital

Aims and Objectives: To determine the age& sex incidence in peptic ulcer perforation patients. To determine the incidence of perioperative complications. To analyse the effect of time of presentation on morbidity and mortality in patients with peptic ulcer perforation. To analyse various factors effecting the morbidity and mortality in patients with peptic ulcer perforation. Material and Methods: This is a 1 year prospective study which includes 50 cases, i. e. , at Kamineni Institute of Medical Sciences Narketpally. All the 50 cases were admitted in KIMS Narketpally diagnosed with gastric& duodenal ulcer perforation were included in the study. All the cases admitted in KIMS Narketpally diagnosed with gastric ulcer perforation. Results: This is a prospective analysis of outcome in patients with peptic ulcer perforation. Out of 50 patients 90 % are male and 10 % are female.74 % presented early and 26 % presented late 36 % are with co-morbities.22 % used NSAIDS 20 % had PUD 88 % have addictions 2 % had preoperative shock and 2 % had AKI.66 % had Duodenum ulcer and 34 % had gastric ulcer 8 % have wound infection, 10 % had ileus and 4 % had leak 10 % had pulmonary complications 2 % had wound dehiscence, 8 % had sepsis and 2 % died. Conclusion: Among 50 patients, most common postoperative complication was Ileus and pulmonary complications in about 10 % patients followed by Wound infection and sepsis. Risk factors for morbidity and mortality in perforated peptic ulcer were age 65 years, associated medical illness, alcohol consumption, duration of perforation more than 24 hours before surgery and presence of shock on admission.