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The rate of liver impairment, character of bacteremia and serum bactericidal activity in patients with cirrhosis

Journal: Medicni perspektivi (Vol.19, No. 2)

Publication Date:

Authors : ; ; ; ; ;

Page : 39-45

Keywords : liver cirrhosis; liver impairment; bacteremia; serum bactericidal activity;

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Abstract

Dependence of prevalence and severity of bacteremia on the rate of liver impairment, serum bactericidal activity (SBA), and serum concentrations of C-reactive protein (CRP) and granulocyte colony-stimulating factor (G-CSF) in 80 hospitalized patients with liver cirrhosis (LC) have been studied. It was shown that risk factors associated with the development of bacteremia are high by Child-Pugh score and low SBA, CRP and G-CSF levels. Patients with LC, class A had the highest SBA, CRP and G-CSF levels. Still 14,3% of them developed less severe bacteremia associated with one type of microorganisms isolated from blood. Patients with LC, class B had intermediate SBA, CRP and G-CSF levels. They developed severe bacteremia in 52,6% of cases and less severe bacteremia ? in 21,1% of cases. Patients with LC, class C had low SBA, CRP and G-CSF levels. They developed severe bacteremia in 62,5% of cases and less severe bacteremia ? in 25% of cases.

Last modified: 2014-12-19 17:36:02