Evaluation of Contrast Media Parameters for Pulmonary Angiograph in Sudanese Population using Deferent Multidetector CT Scanning

Aim: To evaluation of contrast media parameters for pulmonary angiograph in Sudanese population using deferent multidetector CT scanning Methods: The study was obtained using a low osmolar nonionic contrast medium. , over a period from 10 months from January 2016 to 13 October 2017, consecutive in patients undergoing contrast enhanced MDCT scanning of the pulmonary angiography for an indication other than suspected PE were identified at a deferent hospital and diagnostical centers in Sudan Khartoum state the patients were selected for study group as this was the population thought to be most at risk and whom was considered most likely that unsuspected PE might be detected, the study includes Sudanese group of a symptomatic patients whom complaining of chest pain were the sample size were 368 patients 179 male and 189 female and the age from 14 to above 65 years Patients were scanned using either a 64, 160 slices (Toshiba Series), 128 slices scanners (Neusoft) 16 slices GE), all study was obtained with power head automati injetor GE-Nemoto CT Dual-Shot injection system, The researcher evaluates the degree of contrast enhancement in the main pulmonary trunk, ascending aorta, and descending aorta was also evaluated by measuring the mean HU on the largest image in a clear cut of the main pulmonary artery bifurcation in a region of interest (ROI) with a diameter equal to half the diameter of the main pulmonary artery, by the same size and same cut ascending, descending aorta was also, this criteria used to define the degree of contrast opacification at this locations Results: CM triggering method between deferent studded MDCT, 160 slices represent 100.0 % automated detection without using manual detection, 128 slices 100.0 % using manual detection without using automated detection, 64 slices 98.5 % using automated detection and 1.5 % using manual detection, and the16 slices 84.4 % using manual detetction and 15.6 % with automated detetction, the mean HU values in pulmonary trunk, ascending and descending aorta with and without slain flush technique, the HU values with using saline flush mean stander deviation (364.3106), (14265), (12660.5) pulmonary trunk, ascending aorta, descending aorta respectively. the HU values without using saline flush (351.6 121), (16887.5), (15480.4) pulmonary trunk, ascending aorta, descending aorta respectively. in 160 slices (4.8 0.4) ml/s, all 128 slices users were use fixed (4.5) ml/s, 64 slices (4 0.1) ml/s and finally 16 slices (4.4 0.3) ml/s, so all MDCT scanner users used variant flow rate minimum 3.0 ml/s and maximum 3.0 ml/s except 128 slices users used fixed flow rate 4.5 ml/s.160 slices represent as the shorter time after injection subsequent 64 slices, 128 slices and finally 16 slices which have the longest time after injection and attributable to flow rate and the used amount of contrast media used volume of CM between deferent MDCT which represent 16 slices MDCT as the highest volume of CM users and 64 slices MDCT as the lowest volume of CM despite that 64 slices have the intermediated flow rate minimum3.5 ml/s maximum.4 ml/s it has the higher mean HU (499.4 77.8) and the highest total scan time (25.2 4.8) which is give grate effect in the dose profile 160 slices (4.8 0.4) ml/s, all 128 slices users were use fixed (4.5) ml/s, 64 slices (4 0.1) ml/s and finally 16 slices (4.4 0.3) ml/s, so all MDCT scanner users used variant flow rate minimum 3.0 ml/s and maximum 3.0 ml/s except 128 slices users used fixed flow rate 4.5 ml/s Conclusion: As CT scanners have evolved, the use of intravascular contrast media has become more complex, Contrast media administration requires more tailoring than in the past. Injection techniques must be carefully evaluated so that injection protocols can be developed that suit the specific needs of the facility. Technologists must recognize the many variables surrounding contrast administration so that they can assist radiologists in developing injection protocols and to ensure that the protocols are appropriately followed The mean HU values were increased when using saline flush, the used flow rate in the study in all MDCT scanner were deferent even the volume of contrast is small a high flow rate with saline injection following, will enable adequate pulmonary artery contrast enhancement.16 slices MDCT represent as the highest volume of CM users and 64 slices MDCT as the lowest volume of CM in relation to the contrast bolus, the studies mentioned above have shown that a major index to consider is the iodine delivery rate, rather than the total iodine dose.