Diagnostic accuracy of Trucut Needle Biopsy and Fine Needle Aspiration Cytology as Compared with Final Histopathological Examination to Diagnose Breast Lump as Malignant or Benign

Objective- To find out the diagnostic accuracy of Fine Needle Aspiration Cytology (FNAC) and Trucut Needle Biopsy (TCNB) against final histopathological examination in breast lumps suspicious for malignancy. Methodology: Retrospective cross sectional observational study for a duration of 2 years in the department of pathology Pt. JNM Medical College Raipur and associated Dr. BRAM Hospital Raipur (C. G. ). Female patients presented with suspected malignant breast lumps were included in the study. All breast lumpectomy cases were studied and patients previous FNAC and TCNB report obtained and their results were analyzed and re-categorized as C1, C2, C3, C4 and C5 for FNAC; B1, B2, B3, B4 and B5 for TCNB. Results- Total 110 cases of suspected malignant breast lump were taken in the study. Malignant cases were found to be maximum 39.6 % in age group between 41 to 50 years while benign cases were maximum 40 % among age group 31 to 40 years. In this study sensitivity, specificity, positive predictive value and negative predictive value for FNAC were 71.3 %, 100 %, 100 % and 43.9 % respectively while for TCNB were 97.4 %, 100 %, 100 % and 91.3 % respectively. Both FNAC and TCNB were found 100 % specific in diagnosing malignant breast lesions and both procedure having similar positive predictive value of 100 %. Conclusion- TCNB is more sensitive than FNAC in diagnosing malignant breast lumps. Both the procedures having 100 % specificity. False negativity rate is more in FNAC.