Analysis of Anti-Mullerian Hormone along Different Clinical Parameters in Infertile Women Undergoing Intracytoplasmic Sperm Injection
Journal: International Journal of Science and Research (IJSR) (Vol.8, No. 6)Publication Date: 2019-06-05
Authors : Sarwah Razzaq Shareef; Chiman Khudur Mawlood;
Page : 1800-1806
Keywords : Anti-Mullerian hormone; in vitro fertilization; infertility; intracytoplasmic sperm injection;
Abstract
Anti-Mullerian hormone (AMH) is a homodimeric disulfide-linked glycoprotein that controls not only different reproductive functions in both sexes but also outcomes of ovarian hyperstimulation and syndrome, live birth rate following in vitro fertilization, and cancer prognosis. This study was therefore conducted to analyze changes in AMH serum concentration in patients, with different clinical parameters, undergoing intracytoplasmic sperm injection. In this retrospective study, 51 patients were hyperstimulated with follitropin alfa and cetrorelix before undergoing oocyte recovery, ICIS, and embryo transfer. Levels of AMH were analyzed on cycle day two before the ovarian hyperstimulation, and clinical pregnancy outcomes were evaluated five weeks following embryo transfer. Our analysis showed that AMH levels were significantly lower in infertile women with BMIgreater than30 (P
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