Evaluation of Anthelmintic Activity of Holoptelea Integrifolia

Holoptelea intergrifolia (Roxb) Planch (Ulmaceae) is commonly known as Indian elm, kanju. It is widely distributed throughout India in deciduous forests. In traditional system of medicine, bark and leaves are used as bitter, astringent, acrid, thermogenic, anti-inflammatory, digestive, carminative, laxative, anthelmintic, depurative, repulsive, urinary astringent and in rheumatism. The present study was carried out to investigate the anthelmintic activities of different extracts of benzene, chloroform, methanol and aqueous extracts of the stem bark of Holoptelea integrifolia against adult earth worm Pheretima posthuma. The time taken for each worm for paralysis and death were determined. The results were compared with the results of standard i. e. Piperazine citrate. Methanolic and aqueous extracts both were found to possess significant anthelmintic activity in comparison to the standard drug. Both the extract showed dose dependent anthelmintic activity.