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Syntheses, Characterization and Antimicrobial Activity of Triphenyl Antimony (V) Derivatives of Heterocyclic Dithiocarbamate

Journal: International Journal of Science and Research (IJSR) (Vol.8, No. 7)

Publication Date:

Authors : ; ; ;

Page : 1601-1606

Keywords : triphenyl antimony V derivatives; heterocyclic dithiocarbamates; antimicrobial activity; spectral studies; anisobidante manner;

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Abstract

The reactions of Ph3SbBr2 with the sodium salt of heterocyclic dithiocarbamates in 1: 1 and 1: 2 stoichiometries yield the derivatives and, respectively [Where X = greater thanCH2 (Pipdtc) (1, 6), greater thanCH�CH3 (4-MePipdtc) (2, 7), greater thanO (Morphdtc) (3, 8), greater thanN-CH3 (N-mePzdtc) (4, 9) and greater thanNH (Pzdtc) (5, 10)]. All the newly synthesized compounds have been characterized by elemental analyses, molecular weight measurements and spectral (IR, 1H& 13C NMR and ESI mass) studies. Sodium salt of heterocyclic dithiocarbamates and their corresponding triphenyl antimony (V) bromo- and bis (dithiocarbamate) derivatives have also been screened for their antimicrobial activity against bacteria S. aureus (gram +ve), E. coli, Z. mobilies and P. aeruginosa (gram �ve) and fungi ( P. chrysosprium, A. solani, P. chrysogenum and F. oxisporum).

Last modified: 2021-06-28 18:20:06