Bartters Syndrome in Pregnancy: A Case Report and Review

Bartter's syndrome is a rare autosomal recessive disorder characterized by hypokalemia, hyperaldosteronism, sodium wasting, normal blood pressure, hypochloremic alkalosis, and hyperplasia of the juxtaglomerular apparatus. We present a 28-year-old Indian nulliparous patient who was referred to our hospital at 16 weeks' gestation. Patient was known case of Hyperthyroidism diagnosed 18 months ago and was being treated with Propylthiouracil. She presented with Vomiting followed by ascending quadriparesis. She required increasing potassium supplementation. She developed hypomagnesemia which necessitated magnesium therapy. Patient suffered intrauterine death of her fetus. Bartter's syndrome, although extremely rare in pregnancy, requires prompt recognition and careful management, as it may have significant maternal and neonatal implications.