Comparison of Prevalence of Metabolic Syndrome in Obese PCOS Women with Nonobese Pcos Women

OBJECTIVES: The aim of this study is to compare the prevalence of metabolic syndrome in obese PCOSwomen with nonobese PCOS women. PLACE OF STUDY: Gynaecology OPD, Sree Balaji medical college and hospital, Chromepet, Chennai. PERIOD OF STUDY: august 2016 to february 2018 (18 months). STUDY DESIGN: Prospective study. MATERIALS AND METHODS: All reproductive age group women coming to gynaecology out-patient clinic with menstrual irregularities or androgenic features or infertility or obesity are screened for PCOS using Rotterdam criteria. Two hundred and fifty women in reproductive age group, diagnosed as PCOS using rotterdam criteria, are included in the study, after explaining the nature of the study and obtaining informed consent for participating in the study. They are classified into different BMI categories using WHO classification of obesity and then they are subjected to the new IDF criteria for diagnosis of metabolic syndrome. Then the prevalence of MetS is compared between obese PCOS women and nonobese PCOS women. IBM SPSS statistical software version 21 was used for data analysis. P value less than 0.05 was considered as statistically significant. RESULTS: In our study the overall prevalence of metabolic syndrome among all PCOS women is 37.6 %. The prevalence of MetS is only 2.6 % in normal weight PCOS women when compared to 95.7 % in obese PCOS women. Among the PCOS people with waist circumference up to 80cm, only4 (3.8 %) people had metabolic syndrome and among people waist circumference more than 80.1 cm, 90 (62.1 %) people had metabolic syndrome. CONCLUSION: In modern era of economically growing world, there is a rising trend of PCOS and increased practice of sedentary behaviour and lack of physical activity. PCOS per se has evolved as a risk factor for MetS, the overall prevalence of MetS in this study being 37.6 %. In our study the prevalence of MetS is only 2.6 % in normal weight PCOS women when compared to 95.7 % in obese PCOS women. Thus it can be concluded that obese PCOS women are at more risk of developing MetS than nonobese PCOS women. So, it creates an important issue when dealing with PCOS patients, especially obese PCOS patients and it is a treating doctor�s duty to take it as an opportunity to screen for metabolic syndrome and advice on healthy diet, physical activity, weight reduction.