A Study of Association of Serum Vitamin D Level with Hypertension in GNRC Hospital, Dispur, ASSAM

Background: Evidence suggests that low levels of Vitamin D may adversely affect the cardiovascular (CV) system. Several studies have been done regarding the relation and possible causative role of Vitamin D in CV disorders and its well-known risk factors; The aims were as follows: (1) To study the relation between serum Vitamin D level between nonhypertensive and hypertensive patients. (2) To study the relation of serum Vitamin D levels in patients with isolated systolic hypertension (ISH), isolated diastolic hypertension, systolo-diastolic hypertension, and their comparison with nonhypertensives. Materials and Methods: A cross-sectional study was conducted with 154 patients attending cardiology OPD of GNRC Hospital of Dispur, ASSAM from June 2016 to June 2019. The Vitamin D was measured by direct ELISA method. Blood pressure (BP) measurements were done. Statistical analysis was done by using SPSS 16.0 for Windows. Results: The Vitamin D level in the hypertensive group was 22.36 � 12.64; ISH Group was 22.04 � 14.26; the isolated diastolic hypertension (IDH) Group was 18.82 � 0.00; Then, the mean value of Vitamin D in nonhypertensive Group (27.47 � 13.43) was significantly (P less than 0.05) higher than IDH, SDH, and the hypertensive as a whole groups. The relation with ISH Group also reached near significance (P = 0.074). There was a negative correlation with BP and serum Vitamin D. This remained statistically significant (P = 0.044) for systolic BP (SBP) and near significant (P = 0.075) for mean arterial pressure. In population having serum Vitamin D