The Study of Multidrug Resistance Escherichia Coli in Drinking Water Samples from 3rd, 5th and 11th Districts of Kabul City

Antibiotic resistance in pathogenic Bacteria is a serious public health issue. Various factors contribute to the spread of antibiotic resistance micro organisms in the environment. This study was aimed for detection of multi drug resistance Escherichia Coli in drinking water samples from 3rd.5th and 11th districts of Kabul city. This study was done in Descriptive Cross Sectional method during January upon December of 2019. Water sample is taken in Simple Random Sampling. The population size of drinking water sampling is N=378 and by using of Epi info programme, the water sample is selected and so, the sample size of water sample is 378 samples, therefore 126 water sample from house hold, 126 samples from supplies and 126 samples from collection tankers of 3rd, 5th and 11th districts of Kabul city{Tables 1, 2, 3}.126 Samples of drinking water from districts 3, 5 and 11th of Kabul city were collected in a sterile bottle from various parts of each district of Kabul city bringing into Microbiology Department and growing it in mac-conkey agar { Tables4, 5, 6 }. the collected data is by using of MS excel and SPSS software was analyzed and Statics tests were established upon them. out of 378 samples collected in 243 (64.3 %) Escherichia coli were isolated and 135 (35.7 %) samples were free of E. coli. Maximum resistance was observed against Nalidixic acid (64.3 %) followed by ampicilline) 59.5 %), Ciprofloxacine, ( 57.1 % ( and gentamycine ( 5.7 % ( and ceftriaxone (4.7 % (. It is also remarkable that percentage of Escherichia coli in different sources of 3rd.5th and 11th districts of Kabul city such as house hold, supplies and collection tanker was as follows: 16.6 %, 19 % and 28.57 % { Tables7, 8, 9, 10}. in this study it was found, that contaminated percentage of drinking water in 3rd, 5th and 11th district of Kabul city was relatively low than other Asian and African countries. The cause of its contrast may be due to sample size differene and aslo detection of multidrug resistance Escherichia coli could be different from one country into another country.