The Role of Calcitriol in Chronic Kidney Disease Mineral Bone Disorder in Dialysis Patients
Journal: International Journal of Science and Research (IJSR) (Vol.8, No. 11)Publication Date: 2019-11-05
Authors : S. Niharika Reddy;
Page : 47-50
Keywords : CKD-MBD; Calcitriol; calcium; phosphorous;
Abstract
Chronic kidney disease-mineral bone disorder (CKD-MBD) is a systemic disorder of mineral and bone metabolism. It is a systemic condition that manifests as abnormalities in parathyroid hormone (PTH), calcium (Ca), phosphorus (P), and vitamin D metabolism, with associated bone abnormalities and ectopic calcification. CKD-MBD is associated with vascular calcification and cardiovascular disease (CVD), and these conditions are closely related to an increased mortality rate. Guidelines for the treatment of CKD-MBD have been published by Disease Outcomes Quality Initiative (DOQI) and Kidney Disease Improving Global Outcomes (KDIGO).
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