To Study the Visual Outcome of Therapeutic Penetrating Keratoplasty in a Tertiary Care Center

Introduction: Corneal ulcer is the major cause of visual impairment and blindness. Lack of accessibility of eye care, delayed or inappropriate treatment, and microbes not responding to antimicrobial therapy may result in a large or perforated ulcer which will necessitate therapeutic penetrating keratoplasty (TPK). The procedure is meant to terminate or reduce an actively infectious corneal disease or repair an anatomic defect in the cornea. Penetrating keratoplasty constitutes a significant proportion of keratoplasty performed in developing countries. Objective: To find out the visual outcome of therapeutic penetrating keratoplasty for infective keratitis. Materials And Methods: A hospital based interventional study, carried out in department of Ophthalmology for 1 year and penetrating keratoplasty was performed in cases of recalcitrant microbial keratitis with impending perforation and outcome was noted. Results: In the present study 10 cases were enrolled. The maximum number of patients that is 7 patients were in the age group of 51-60 year (70 %) whereas the least cases found in 41-50 years of age group. Out of 10 cases, 60 % were male and 40 % were female. Active keratitis were maximum trauma in 6 cases (60 %) which was a major risk factor. Culture positive was seen maximum for fungus in 6 (60 %) case. Preoperative UCVA was PL+ PR accurate in maximum 5 (50 %) cases. Postoperative BCVA was seen maximum in 6 (60 %) i. e.