Assessment of Central Sensitization using Pain Pressure Threshold and Its Association with Disability and Quality of Life in Patients with Knee Osteoarthritis

Osteoarthritis (OA) is associated with increased pain, disability, and functional limitations. The chronic pain processing in OA could be associated with pathophysiological condition called central sensitization. Our study objectives were to compare PPT (Pressure pain threshold) in OA patients and in age sex matched healthy individuals and correlating their PPT with pain sensitivity and quality of life. Study design was Crossectional observational comparative study.35 participants in each group were included& Assessed for PPT measurements using sphygmomanometer cuff algometry at dermatomes, myotomes, sclerotomes around knee. Pain intensity was assessd by NRS, QOL life by KOOS (KNEE INJURY AND OSTEOARTHRITIS OUTCOME SCORE). Results& conclusions: PPT values were significantly lower in the knee OA patients versus the healthy controls (P