Phytochemical Analysis and Antibacterial Activities of Pimpinella tirupatiensis against Bacillus subtilis, Klebsiella pneumoniae, Proteus vulgaris and Pseudomonas aeruginosa

The human culture directly or indirectly was influenced by plants from the time immemorial. The progress of human civilization was accompanied by the use of plants and nature throughout the ages. Plants are fundamental to almost all life on earth providing protection and sustenance to other organisms. Plants which are natures precious gift to mankind have health improving properties. Nature has served as a rich repository of medicinal plants for thousands of years and an improve number of modern drugs have been isolated from natural sources notably of plant origin. Herbal medicine, based on their traditional uses in the form of powders, liquids or mixtures, has been the basis of treatment for various ailments in India since ancient times. There are numerous references for the use of plants as therapeutic agents both in the works of Indian medicine and other works of antiquity. Plants have played a major role as the basic source for the establishment and enhancing the economy of developing countries like India. To elevate the medicinal properties, root tubers of Pimpinella tirupatiensis were collected from different localities of tirumal hills, Eastern Ghats, Andhra Pradesh, India. The methanolic extracts of root tubers were qualitatively screened for phytochemicals by using standard procedures which revealed the presence of various important bioactive chemical entities. Antibacterial activity of the methanolic extracts of root tubers were evaluated against Bacillus subtilis, Klebsiella pneumoniae and Proteus vulgaris, Pseudomonas aeruginosa. The methanolic extracts of root tubers have exhibited significant broad spectrum antibacterial activities.