Study of HIV Related Opportunistic Infections and its Correlation with CD4 Counts

Introduction Number of HIV cases increasing in poor countries like India despite of successful implementation of control programs. Mortality in HIV cases because of OIs and other malignancy. This is retrospective study to evaluate HIV related OIs and its correlation with CD4 counts. Methods A prospective observational study was conducted for 6 month period in ART centre, Hamidia hospital, Gandhi medical college Bhopal from February 2017 to August 2017 after taking informed consent. All participants underwent detailed clinical examination and clinical sample were collected from HIV positive patients and performed various staining and culture methods. CD4 count were estimated by FACS. Results In this study most common OIs was tuberculosis (65 %) in HIV positive patients followed by candidiasis ( 57.5 %), respiratory tract infections (47.5 %), gastro intestinal infections (40 %) and meningitis (35 %). Most of mortality was recorded in Hiv positive cases with CD4 counts& lt, 50 cells/ l. Conclusion This study concluded that incidence of HIV related OIs high in low CD4 counts so early diagnosis and early treatment of HIV related OIs can increase or improve life expectancy of HIV patients.