Complications of Sodium Bicorbonate Buffered Lignocaine and Hyaluronidase Mixed Lignocaine for Ocular Anaesthesia - A Comparative Study

AIM To compare and evaluate the efficacy, duration of action and complications of 7.5 % Sodium bicarbonate buffered lignocaine with Hyaluronidase mixed lignocaine used as Regional anaesthesia in cataract surgery. DESIGN A Prospective, interventional, comparative study. PARTICIPANTS Three hundred cataract patients were involved in this prospective, interventional and comparative study. METHODS Two groups of patients (Group I and Group II) with 150 patients in each. The patients included in this study were examined for ocular and systemic diseases. The required pre-operative investigations for cataract surgery was done. Post-operative photographs were taken for documentation. Group I patients had 7.5 % Sodium bicarbonate buffered lignocaine and group II patients had Hyaluronidase mixed lignocaine used as Regional anaesthesia RESULTS Time of onset of anaesthesia and akinesia was 6-10 minutes for Group 1 and 5minutes for Group II patients. More number of patients in Group I had Intra operative complications like Repeat block, Conjunctival Chemosis, Persistant eye movements (akinesia not achieved) and also Post-operative complications like Ptosis and Lid edema than in Group II. Analgesia was better in Group I than in Group II. CONCLUSION All Complications like chemosis, lid edema and ptosis was more in sodium bicarbonate buffered lignocaine group resolved totally with maximum period being 4 days and one Ptosis resolved in 2 weeks. None of them had visual or systemic side effects. The advantagein using Sodium Bicarbonate buffered Lignocaine was cost effective safe and is readily available.