Role of B Type Natriuretic Peptide in Predicting Development of Ventricular Dysfunction in Patients on Single Chamber Permanent Right Ventricular Pacemaker with Structurally Normal Heart

ROLE OF B TYPE NATRIURETIC PEPTIDE IN PREDICTING DEVELOPMENT OF VENTRICULAR DYSFUNCTION IN PATIENTS ON SINGLE CHAMBER PERMANENT RIGHT VENTRICULAR PACEMAKER WITH STRUCTURALLY NORMAL HEART Dr Girish Narayan Mishra, Consultant Interventional Cardiologist Narayan Medical College and Hospital, Jamuhar dehri Bihar, drgnm80@gmail. com Dr Avadhesh Narayan Khare, Consultant Interventional Cardiologist J. K. hospital and L. N. Medical College, Bhopal, dravadh7aug@gmail. com (Corresponding author) INTRODUCTION It is well known that level of BNP is high in single chamber pacing as compared to dual chamber pacing but whether raised level of BNP can predict development of ventricular dysfunction is not well known. AIMS AND OBJECTIVES 1. Relation between raised BNP and ventricular dysfunction.2. Effect of right ventricular apical pacing on blood level of BNP. STUDY DESIGN prospective, observational study RESULTS AND OBSERVATIONS The measured indices of RV dimension, were comparable between the patients at baseline, and after 3 months and 6 months of pacing. None of the patient developed dilatation of RV basal dimension at 6 months. One patient develop dilatation of RV mid for which p value was not significant (p=1.0). At baseline evaluation for interventricular dyssynchrony, none of the patient had interventricular dyssynchrony. After 3 months, 11.76 % of the patients developed interventricular dysynchrony, and after six months of pacing, 33.33 % of the patients had (p