Histolopathology and Proteotoxicity Studies in the Liver Samples of Freshwater Fish Channa punctatus (Bloch), on Exposure to Fungicide, Bordeaux Mixture

Fish are one of the major sources of protein for human beings and the nutritional value of fish depends on their biochemical composition like protein, amino acids, vitamins, mineral contents, etc. The present study was intended to evaluate the impact of pesticide toxicity stress symptoms in fresh water fish Channa punctatus. The toxicity of Bordeaux mixture, a fungicide was assessed by exposing the experimental species Channa punctatus to sub lethal concentration of Bordeaux mixture under static bioassay condition. From the experiments done, it was observed that at. . . . . . ppm concentration of Bordeaux mixture, 50 % mortality occurred. After 96 hrs of exposure, the fish tissue samples were collected from liver. The samples were analyzed for histopathological changes as well as alterations in the protein profile using SDS PAGE technique. Noticeable degenerative histopathological changes were observed in the liver of Channa punctatus exposed to Bordeaux mixture. The protein profile also found to be varied much from the normal liver samples.