Antibiotic for Antimicrobial Finishing of the Textiles

Novel methods of dyeing has been introduced to get better results as compared to conventional dyeing. The present study was carried out for dyeing cellulosic fabric using bi-functional reactive dye and analysing the dye fixing ability of the reactive dyeing in presence of Amoxicillin 250mg. The results were compared with the conventional dyeing methods. It is observed that the dye fixing in presence of antibiotics gives better results as compared to conventional dyeing. Amoxicillin is an antibiotic useful for the treatment of bacterial infections. It is a moderate spectrum, bacteriolytic, -lactum antibiotic in the aminopenicillin family used to treat susceptible gram positive and gram negative bacteria. Antibiotics which play important role in treating several diseases become a colossal problem during disposal for various reasons. Amoxicillin is susceptible to degradation by -lactamase-producing bacteria, which are resistant to a broad spectrum of -lactam antibiotics, such as penicillin, for this reason, it is often combined with clavulanic acid, a -lactamase inhibitor. This increases effectiveness by reducing its susceptibility to -lactamase resistance. Amoxicillin has two ionizable groups in the physiological range (the amino group in -position to the amide carbonyl group and the carboxyl group). Amoxicillin has a good pharmacokinetics profile with bioavailability of 95 % if taken orally, its halflife is 61.3minutes and it is excreted by the renal and less than 30 % bio- transformed in the liver. So in the present study we are using expired antibiotic drugs instead of alkali for fixation of reactive dye in dyeing. The work depicts a successful attempt to provide antimicrobial finish to the cotton fabric with outdated antibiotic amoxycilin. This method of unused medicines valorisation can solve two major environmental and economic problems limitation of environmental pollution with pharmaceutically active compounds and reduction of the disposal costs of expired antibiotics.