Endometrial Cancer in Young Tunisian Women about four Cases

Objective To report a series of 4 cases of endometrial cancer in young women and to study its peculiarities through our series and a recent review of the literature. Patients and methods This is a retrospective study of the medical records of 4 cases followed for endometrial cancer at an age under 33 years. Results the age of our patients was respectively 27, 27, 30 and 32 years old. Three patients had metabolic syndrome and one patient had a family history of cancer of the colon and pancreas. All our patients were childless. Persistent metrorrhagia and pelvic pain were the main circumstances of discovery. The diagnosis was made preoperatively by endometrial sampling under hysteroscopy in 2 cases and by histological examination after laparotomy for pelvic mass in 2 cases. The tumor was grade 1 or 2 endometrial carcinoma in 3 cases and carcinosarcoma in 1 case. Surgical treatment was oncological in 3 cases. Radiotherapy with or without chemotherapy was done in all cases. One patient died after 11 months of the discovery of her disease and the other 3 cases have a recurrence-free survival of more than one year. Conclusion The endometrial cancer of young women is often diagnosed with some delay. This cancer differs from that of older women in several ways. The treatment has no particularity except for the desire to preserve fertility.