Proposed Plan to Investigate the Impact of Amniotic Fluid Index on Pregnancy Outcome at Selected Obstetrics&Gynecology Clinics, Jeddah, Saudi Arabia

Background Amniotic fluid is vital to the well fetus. It cushions the fetus from injury, helps to prevent compression of the umbilical cord, and allows room for it to move and grow. The current study amid at introducing a Proposed Plan to Investigate the Impact of Amniotic Fluid Index on Pregnancy Outcome at Selected Obstetrics& Gynecology Clinics, Jeddah, Saudi Arabia. The purposes in its utilization are evaluation of maternal serum interleukin-6 (il-6) as an early marker of subclinical chorioamnionitis in patients with preterm premature rupture of membranes. Hoping to improve maternal and neonatal outcome in PPROM and to bring about changes in management strategies in PPROM. Objective To provide a framework of Proposed Plan to Investigate the Impact of Amniotic Fluid Index on Pregnancy Outcome at Selected Obstetrics& Gynecology Clinics, Jeddah, Saudi Arabia. Method An experimental research design is proposed to be utilized in the current study in which the participants will be divided into two groups a study group presenting with PPROM between 24 and 34 weeks gestation and a control group of healthy pregnant women without PPROM (matched for age, parity, and gestational age. Serum IL-6 levels will be determined by solid-phase sandwich enzyme-linked immunosorbent assay. Results This study finding will include the data related to evaluation the clinical usefulness of maternal serum IL-6 as early marker for detection of subclinical chorioamnionitis in patients with preterm premature rupture of membranes. Secondly to compare interleukin 6 with total leukocyte count and C reactive protein as a method for earlier detection of subclinical chorioamnionitis in patients with preterm premature rupture of membranes. Conclusions The current study results aiming to reveal the data beyond the achievement the objectives Assessment of need for additional markers in the maternal serum, simpler and less invasive than amniocentesis to predict intrauterine infection. Secondly, Early diagnosis of subclinical infection and inflammation that may therefore aid clinicians to institute interventions focusing on adverse outcomes. Finally, Subjective and objective assessment of early onset of complications and/or side effects.