Construction and Research of National Cross - regional Supply Chain Network Based on New Silk Road

China put forward the concept of Silk Road Economic Belt is a strategic initiative of cooperation with a global vision. Silk Road Economic Belt provides a good opportunity to strengthen economic and cultural exchanges with the countries along the line, open up the international market, the development of foreign trade, For the development of domestic industries to provide a broader market space. So pay attention to the advantages of regional cooperation, from the cross-regional supply chain to start, concerned about the economic cooperation between China and Asian& European countries, regional integration in the product, logistics and capital advantages, improve the optimal allocation of resources. In this paper, the Silk Road economic belt as the main line, along the country as a node to discuss the establishment of cross-regional supply chain. Analyze the advantages of each node, and study how to strengthen the optimization of the whole supply chain, and how to make the flow of information flow, logistics and capital flow fast, so as to accelerate the circulation of the whole supply chain,. So as to obtain the actual boosting effect of the supply chain on the economic development of each country.