A Comparison between Intrathecal Bupivacaine alone and Intrathecal Bupivacaine in Combination with Nalbuphine for Post-Operative Analgesia

Background In this study, we compared intrathecal Bupivacaine alone and intrathecal Bupivacaine in combination with Nalbuphine in terms of post-operative analgesia. Methods 50 patients of ASA physical status I& II, aged 16-55 years, of either gender, undergoing elective lower abdominal and lower limb orthopaedic surgeries under subarachnoid block were enrolled in this study. Patients were divided into 2 groups of 25 each. Assessment of motor and sensory blockade was done by Bromage scale and pin-prick method. Post-operative analgesia was assessed by VAS score. Results There is no significant difference between the 2 groups for onset of motor and sensory blockade. Two segment regression time of sensory blockade and duration of effective analgesia were prolonged in the Nalbuphine group. Conclusion In this study we found that intrathecal Nalbuphine in the dose of 0.8mg along with Bupivacaine produces prolonged post-operative analgesia without increased incidence of side effects.