Comparison the Activity of ALT Enzyme in Saliva of Periodontitis Patients with Control and Determine the Effect of ZnONPs on its Activity

The optical and structural properties of the zinc oxide nanoparticles [ZnO NPs] have been studied using SEM and [UV-Vis] spectrophotometer. The produced nanoparticles have molecules size 80 nm and spherical in shape. The zinc oxide NPs effect was investigated on Alanine Transaminase [ALT] activity in the saliva of 20 patients with chronic periodontitis disease as compared with 15 healthy persons with age range from 30-60 years for all groups. The consequences for this study was there is significant elevation in activity of salivary alanine transaminase enzyme chronic periodontitis patients as compared to control group, and there is significant elevation in the activity of ALT by the effect of ZnONPs when compare with the same chronic periodontitis patients without using ZnONPs, in conclusion ZnONPs causes activation to ALT enzyme activity.