Estimation of Salivary Cadmium, Calcium and Manganese Level in Periodontal Disease Patients

Background Periodontal disease is a common, multi-factorial, chronic inflammatory disease that involves degradation of tissues that support teeth, including alveolar bone. Many salivary biochemical markers was to detect inflammatory changes in its early stages is useful. The objective of this investigation was to estimate the concentrations of the Cadmium (Cd), Calcium (Ca) and Manganese (Mn) in saliva of periodontal disease patients and compare the results with the concentrations of these elements in control group. Materials and methods This study include 24 saliva samples for both groups (chronic periodontitis patients and healthy control). All the three salivary elements (Cadmium, Calcium and Manganese) were determined by Flame Atomic Absorption Spectrophotometer using standardized procedure by air acetylene. Results The results of this study show highly significant difference between chronic periodontitis patients and healthy control subjects in concentration of all the salivary elements (Cadmium, Calcium and Manganese). There was positive correlation between salivary Ca and Cd in two groups but the correlation between Ca and Mn and the correlation between Cd and Mn was negative correlation. Conclusion there was difference in concentration of salivary concentration of Cd, Ca and Mn between chronic periodontitis patients and control subjects.