Antifertility Activity of Different Extracts of Mimosa Pudica Linn Leaves in Female Rats

Alcolholic, water and petroleum ether extracts of Mimosa pudica Linn leaves was screened for their antifertility activity at the doses of 50, 100, 150mg/KG body weight in female rats. Oral administration of 150mg/kg body weight of all extracts for 1-7 days of post coitum was found to be optimum and most effective dose for antifertility activity. At 50mg/kg body weight implantation sites were observed with water, alcoholic and petroleum ether treated group showing 40, 80 and 40 % antifertility activity. Maximum antifertility was observed after administration of the extract group at a dose of 150mg/kg body wt. From day 1-7 of pregnancy showing 80, 100 % antifertility activity. It is well established that the inhibition of implantation in albino rats is due to imbalance of progesterone, estrogen ratio.