Antiglycemic Activity of Endophytic Fungi from Selected Medicinal Plants by Alpha-Amylase Inhibition Method

The aim of this work was to evaluate the inhibitory activities of ethylacetate extracts of endophytic fungi isolated from tulsi and aloe vera by alpha amylase inhibition method. Diabetes mellitus is a clinical condition characterized by hyperglycemia in which an elevated amount of glucose circulates in the blood plasma. Alpha amylase inhibitors are used to achieve greater control over hyperglycemia in type 2 diabetes mellitus. The present study intends to screen novel alpha amylase inhibitors from natural sources like endophytic fungi from medicinal plants in order to minimize the toxicity and side effects of the inhibitors currently used to control hyperglycemia.