Association between Gram-Negative Enteric Rods, Porphyromonas gingivalis and Changes in Clinical Parameters in Chronic Periodontitis: An Observational Study

The correlation between Gram negative enteric rods and Porphyromonas gingivalis in periodontal diseases has received little attention in the literature. The objective of this study was to investigate the association between gram negative enteric rods and Porphyromonas gingivalis and changes in clinical parameters in chronic periodontitis subjects. Occurrence of Gram negative enteric rods, Porphyromonas gingivalis and clinical parameters were examined in 30 subjects with chronic periodontitis. Sub gingival plaque samples were collected from the deepest periodontal pocket and transported in thyoglycolate broth and organisms were cultured. Chi-square, Mann-Whitney and Spearman rank correlation coefficient were used to assess the clinical data. Gram negative enteric rods, Porphyromonas gingivalis were detected in 20 subjects. There were significantly positive correlations between Gram negative enteric rods, Porphyromonas gingivalis and bleeding on probing, probing depth, clinical attachment loss. This study suggests that presence of enteric rods and Porphyromonas gingivalis were related to adverse periodontal conditions. These results could have an impact on periodontal treatment and should be taken into account in the mechanical and antimicrobial treatment of periodontal disease in some populations.