Intracranial Chondroma - A Rare Case Report

A 30 years female presented with lobulated extraaxial mass lesion along left high convexity. It is predominantly hyperintense on T2 W1& 180 to hypointense in T1W1. Mild heterogeneous enhancement noted on contrast study. Foci of T2 shortening are noted within suggestive of calcification measuring 57x72x36 mm. Intraoperatively, the tumor was extraaxial, avascular, firm to hard attached to dura. Histologically, a tumor composed of lobules of amitotic chondrocytes variably showing mild nuclear enlargement with small nucleoli within well-formed formed lacunae. The intervening stroma is scanty and shows presence of thin walled blood vessels. There is no evidence of atypical cells, multinucleated or mitotic activity. Another differential diagnosis is low-grade chondrosarcoma, showed that a combination of five parameters (high cellularity, presence of host bone entrapment open chromatin, mucoid matrix quality, and age above 45 years) allowed optimal differentiation between enchondromas and chondrosarcomas grade I. Complete resection is the treatment of choice when the lesion is amenable to total removal. On conclusion chondromas are benign tumors that arise from skull base but may arise from convexity as well. Complete surgical resection is the treatment of choice. Histological differentiation from low grade / chondrosarcoma-1 is important.