Comparison of Screening for Hyperglycemia in Pregnancy by OGCT v/s HBA1C

Aims and Objectives To compare HBA1C as a screening test to diagnose GDM with OGCT Background India, being a high risk group for GDM needs a screening program for early diagnosis and to initiate treatment at the earliest. Owing to the many adverse effects of GDM on the mother and the fetus, it makes it of utmost importance to formulte a method. Thus, this study is undertaken to analyse the available modalities to screen antenatal patients and to use the most accurate one, to routinely screen for GDM. HBA1C being a more convenient method, must be evaluated for its usefulness in screening of GDM Methodology This study was undertaken over a period of 2 years, between October 2015 to September 2017, In department of Obstetrics and Gynaecology at Father Muller Medical College, Mangalore, Karnataka 100 women attending the Antenatal clinic in FMMC were enrolled in the study. Consents were taken, and blood drawn for OGCT and HBA1C. The same patients were then subjected to OGTT. Test results were then obtained from biochemistry laboratory records and patients were diagnosed to either be cases of gestational Diabetes mellitus or not depending on the OGTT results. The relation between the OGCT and HBA1C results of these patients and the carbohydrate tolerance status was then established following subjecting the results to statistical analysis. Results On statistical analysis it was identified that OGCT was a better screening test for GDM in comparison to HBA1C with the following values Sensitivity Specificity PPV NPV P value OGCT 78.60 % 70.50 % 77.20 % 72.10 % less than0.001 HBA1C 55.40 % 61.40 % 64.60 % 58.00 % 0.110 Conclusion To conclude, it was identified that OGCT was a more sensitive, specific screening test and had higher positive and negative predictive value to screen for GDM in high risk groups like antenatal patients in India. GDM, HBA1C, OGCT