Synthesis, Characterization and Evaluation the Biological Activity of New Payrazolo{3,4 d} Pyrimidine Derivatives

Allopurinol derivative were prepared by reacting the allopurinol with chloroacetyl chloride in the presence triethylamine as an catalyst and diethylether as a solvent gave the (1-chloroacetyl) -2-Hydropyrazolo{3, 4-d}pyrimidine-4-one which reaction with substituted 2-amino benzothiazole under certain conditions to give new compounds (A-A10) and reaction of 5-substituted-2-amino-1, 3, 4-oxadiazolein in the presence of potassium carbonate anhydrous to give new compounds (A21-A30) respectively. The chemical structure synthesis compound were identified by spectral methods their (FT-IR and1H- NMR) and measurement some of its physical properties. The synthesized compoundS were screened for antibacterial activity.