To Evaluate Ocular Surface Abnormalities in Eyes with Pterygium: Role of Conjunctival Impressioncytology

To evaluate ocular surface abnormalities in eyes with pterygium Role of conjunctival impression cytology Himanshu Kumar, Snigdha Sen, Tirupati Nath, Jyotsana singh, Deepa Rani Department of ophthalmology, Sarojini Naidu Medical College, Agra Mob no.9452561207 Email id drjoylax2013@gmail. com Aim To study ocular surface abnormalities in eyes with primary and recurrent pterygium Conjunctival impression cytology was explored as a tool for the assessment of the cytological changes. Materials and methods A comparative case control study was undertaken to evaluate ocular surface disorders in pterygium.29 eyes with primary pterygium and 9 eyes with recurrent pterygium were enrolled. Normal eye of the patients was taken as control. Patients were evaluated for the tear film break up time (TBUT), schirrmers test and their normal control values. Pre and post op values were also compared. The spectrum of changes in cytomorphology was studied using conjunctival impression cytology. Results Tear film breakup time and schirmers strip wetting were found to be statistically significant in pterygium eyes as compared to their normal control eye in both the pterygium groups as all the values were found to be highly statistically significant. In the post op period TBUT and schirmers showed significant difference in both primary and recurrent pterygium. On cytomorphology squamous metaplasia and pyknotic changes in nuclei of different grades were observed more frequently in eyes with pterygium as compared to control. Comparison between primary and recurrent pterygium showed statistical significant value of TBUT (p valueless than.0001) and schrimers value (p valueless than.0002) Conclusion We conclude that aqueous tear film deficiency leading to ocular surface disorders brings about a change at the cytological level too. Key words Primary pterygium, Recurrent pterygium, Impression cytology