Assessment of Graft Survival after Penetrating Keratoplasty and Study of Graft Failure Causes in our Series

Aim- Assessment of graft survival after Penetrating Keratoplasty and study of the causes of graft failure in our series. Study design- Prospective non comparative hospital based study. Methods and materials Total 60 Penetrating Keratoplasty cases were done and followed during the period from August 2015 to July 2017 at SNMC, AGRA, by assessing the graft clarity, visual acuity and by slit lamp examining the patients for possible causes of graft failure. Results After 1 year follow up graft clarity were 4+ in 7 cases (14 %), 3+ in 11 cases (22 %), 2+in 8 cases (16 %), 1+ in 10 cases (20 %) and 0 in 14 cases (28 %) graft were opaque. Visual acuity at 1 year follow up were between 6/6 6/12, 6 cases (12 %), VA between 6/18 -6/60, 14 cases (28 %), VA between 5/6o- FCCF 16 cases (32 %) and 14 cases (28 %) showing VA between HM- PL+. Conclusion- In our study graft survival was good in young recipients and in patients of corneal opacity with peripheral clear zone of cornea in all quadrants. Corneal neovascularisation was found to be very important cause of graft failure in our study. In others, donor cornea of person above 60 years age, lack of clear zone between opacity and peripheral cornea, preoperative corneal vascularisation, aphakia, re-grafting, postoperative corneal ulcer, dry eye, raised IOP, lack of education, poor socioeconomic profile, poor compliance of drug and lack of proper follow up remains the other causes of graft failure.