Research and Analytical Study of 50 Cases of Acute Pancreatitis

AIMS AND OBJECTIVES: To have some focus on commoner but less studied entity-acute pncreatitis. The research study was designed to recognize the clinical picture of acute pancreatitis in the Indian patients to evaluate common etiologies, role of investigations, outcome of early conservative and and surgical management. METHODS: This study was conducted in 50 patients of acute pancreatitis admitted in government civil hospital.50 cases of acute pancreatitis were admitted and investigated and treated. Observations were made with regards to common presentation, sex distribution, common aetiology and common blood parameters especially s. lipase and s. amylase. Most important point was also taken into consideration of conservative management. RESULTS: The highest incidence of acute pancreatitis was found in the age group of 41 to 60 years followed by the age group of 21 to 40 years. Acute pancreatitis was found more commonly in males compared to females. This may be due to effect of alcohol addiction in males. Surgery is not much useful except in cases of gallstone pancreatitis. In acute pancreatitis, serum lipase level may be elevated more consistently and for longer half-life than serum amylase. Octreotide used in all patients, found helpful in producing symptomatic relief and promoting recovery in mild to moderate cases. CONCLUSION: The clinical pattern of acute pancreatitis varies in different patients. Gallstones continue to be the leading cause of acute pancreatitis in most series. Early ERCP followed by cholecystectomy in the same admission gave excellent results. It is recommended that all patients with pancreatitis should undergo ultrasound within 24 hours of admission as it confirms gallstones and severe pancreatitis.