Antineoplastic Effect of Selected Essential Oil on Ethanol Induced Liver Toxicity IIN Albino Wistar Rats

Liver is a solid glandular organ made up of hepatic lobules separated from one another by connective tissue. Each lobe consists of a mass of polyhedral hepatic cells which are glandular in appearance containing spherical nuclei. A network of blood vessels pierces the lobules. The hepatic cells are arranged in longitudinal cords. It has a gall bladder and secrets bile. Liver is the major metabolic centre and any damage to this organ would subsequently lead to so many physiological disturbances. In the present study antineoplastic effect of Syzygium armaticum and Rosadamacena essential oil on induced liver toxicity in male wistar rats was carried out. From the results it is evident that the administration of N- nitrosodiethylamine considerably reduced the protein non enzyme antioxidants such as glutathione, vitamins C and E and enzymatic antioxidants such glutathione peroxidase, superoxide dismutase and catalase. All the values are statistically significant.