Growth and Characterization of Uric Acid Crystals

Kidney stone (renal calculi) and urinary tract infection is a one of the major disease affecting human being since from ancient period. Urinary tract infection occurs in kidney, urinary bladder and urethra. Crystals of uric acid as well as its sodium salts have been found in the renal tract and urinary bladder. Uric acid is also often found as a constituent of urinary calculi and has a high incidence in nephrolithiasis resulting in most affected kidney function. Uric acid crystals have been grown in single diffusion gel technique. The growth of crystal is studied by FT-IR, FT-Raman, PowderXRDandSEMwithEDX. Many medicinal plants (herbals) are available for dilutic urinary calculi particularlyTribulus terrestris and citrus limon. To verify the inhibitive effect, aqueous extracts of herbals was added along with the supernatant solutions. The growth was measured and compared, with and without the aqueous extracts. Inhibition of Uric acid crystal growth was observed in the herbal extracts.