A case of successful treatment of bilateral acanthamoeba keratitis
Journal: Oftalmologicheskii zhurnal (Vol.2014, No. 3)Publication Date: 2014-06-20
Authors : Drozhzhina G.I.; Zborovskaya A.V.; Ostashevskiy V.L.; Gaydamaka T.B.; Vansovich E.V.; Kurilyuk A.N.;
Page : 119-126
Keywords : KERATITIS; PHOTODYNAMIC THERAPY; METHYLENE BLUE; DIMEKSID;
Abstract
Introduction. Acanthamoeba keratitis is related to a severe pathology of the eye that results from infection of the human body by free-living amoeba in soil. This disease is characterized by loss of the corneal epithelium, stromal thinning, and development of radial keratoneuritis, appearance of the annular infiltration and formation of a central or paracentral corneal abscess. Purpose. To describe a case of successful treatment of bilateral acanthamoeba keratitis where standard therapy was first supplemented with photodynamic therapy (PDT) using methylene blue and dimexid. Material and Methods. There were used test of visual acuity, ophthalmoscopy, microbiological analysis. Results. Complex treatment of bilateral acanthamoeba keratitis, which includes different antiseptics, antifungal, amebicidal drugs, the use of pathogenetic and symptomatic therapy, and the use of PDT with methylene blue and dimexid allowed to stop inflammation and restore vision. Conclusions. In the diagnosis of acanthamoeba keratitis the important role belongs to the anamnesis, biomicroscopy of the cornea with the identification of pseudodendritical figures or recurrent epithelial damage, which are the earliest clinical signs of the disease. Combined treatment of this disease in combination with PDT first used in the oph thalmic practice showed significant therapeutic effect.
Other Latest Articles
- PHYSICAL CHARACTERISTICS OF THE INTERNAL LIMITING MEMBRANE AND THEIR SIGNIFICANCE IN OCULAR SURGERY AND BEYOND
- Ultrastructural changes of the optic nerve in contusion of the eyeball of the mild degree in rabbits
- Peculiarities of the changes of the optic nerve and conjunctiva after exposure to highfrequency electric welding of biological tissues in enucleation of the eyeball in experiment
- Membrane-protective effect of quercetin and lipoate on the retina in streptozotocin diabetes
- Structural changes of the retina, erythropoietin concentration in the vitreous body and peripheral blood in streptozotocin-induced diabetic rats in experiment (intermediate result)
Last modified: 2015-01-20 21:29:55