An Efficient Synthesis and Biological Properties of 2- [ (5-Methoxy-1H- Benzimidazol-2-yl) Sulfanyl] -N-Phenylacetamide Motief
Journal: International Journal of Science and Research (IJSR) (Vol.4, No. 3)Publication Date: 2015-03-05
Authors : Kokila A. Parmar; Ranjit K. Patel;
Page : 1159-1164
Keywords : Acetamide; anti fungal activity; bacterial activity and spectroscopy;
Abstract
A new series of 2- [ (5-methoxy-1H-benzimidazol-2-yl) sulfanyl]-N-phenylacetamide have been synthesized by the condensation 2-mercapto-5-methoxybenzemidazole and 2- chloro N ( Aryl) acetamides. The novel compounds structure has been established on the basis of their substituted N-chloro aryl acetamide derivatives. All the compounds were characterized by Mass, FT-IR, CMR, 1H-NMR spectroscopy as well as elemental analysis. These new compounds were evaluated for their in vitro antibacterial activity and anti fungal activity.
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