A Comparative Study of Lipid Profile in Patients of Hypothyroidism and Diabetes Mellitus

Background A disease due to disorder of the endocrine system is often called as endocrinopathy. Hypothyroidism is a condition characterized by abnormally low thyroid hormone production and diabetes mellitus is also common endocrine disorder which is defined as group of metabolic diseases characterized by hyperglycemia. In this study, 25 patients of clinically established hypothyroidism and 25 patients of diabetes attending the Out Patient Department, Department of Medicine, MDM Hospital (Jodhpur) were evaluated for lipid profile. Results Serum total cholesterol of hypothyroids and diabetic patients showed a highly significant relationship (pless than0.0001 and 0.0002 respectively) as compared to controls. Serum triglycerides showed a very significant relationship (p=0.003 and 0.001 resp. ), serum LDL-c also showed a highly significant relationship (pless than0.0001 and 0.0002 resp. ) while serum VLDL-c of hypothyroid patients showed a significant relationship (p=0.024) and in diabetic patients very significant relationship (p=0.006) as compared to controls. Conclusion Estimation of serum lipid profile is simple, reliable, economic and sensitive that can now be considered as an adjunct in the management of hypothyroidism and diabetes mellitus.