Synthesis and Characterization of Some Coumarin Derivatives
Journal: International Journal of Science and Research (IJSR) (Vol.4, No. 5)Publication Date: 2015-05-05
Authors : Pravin Chowdhary; Vrushali Patil; Ashish Asrondkar; Anil Bobade; Abhay Chowdhary;
Page : 2342-2344
Keywords : Coumarin; anti-microbial activity;
Abstract
A series of coumarin derivatives were synthesized. The present study reveals the synthesis of coumarin derivative in which 4-hydroxycoumarin was reacted with chloroethylacetate in preseance of K2CO3 to form an intermediate which was further treated with hydrazine hydrate to form hydrazino derivative of coumarin and finally the intermediate is condensed by substituted isothiocynate derivatives to form final compound, the synthesized compounds were then Characterized by using FT-IR, 1H-NMR and Mass spectrophotometer, All the compounds were screened for their anti-microbial activity. It was found that the derivatives showed moderate activity as compared to standard
Other Latest Articles
- SOC Based Cryptosystem Implementation Using RC4 and IDEA Algorithm
- Implementation of Edge Detection Technique for Identification and Evaluation of Brain Tumor Metrics in MR Image through Lab VIEW
- Secure Text/Image Data Hiding in Images with Efficient Key Management
- Green Belt Zoning for Ulaanbaatar City
- Signal Processing Algorithm for Vital Sign Extraction of Trapped Victims
Last modified: 2021-06-30 21:46:31