An Insight into the Cell Wall of Mycobacterium Tuberculosis
Journal: International Journal of Science and Research (IJSR) (Vol.4, No. 6)Publication Date: 2015-06-05
Authors : Gaurav Tyagi; SakshiTalwar; Parveen Garg;
Page : 1482-1485
Keywords : Mycobacterium Tuberculosis; Cell Wall; Lipids; Mycolic Acids;
Abstract
Mycobacterium tuberculosis is the most successful pathogen of the present times. It operates via a very complex and indispensable cell wall that is responsible for the persistence and resistance of the bacteria inside the human host. Various kind of lipids are present in mycobacterial cell wall, some unique to Mycobacterium tuberculosis and some present evenly in other mycobacteria as well. Since these lipids play an important role in the successful establishment of infection and are essential for pathogenesis as well they may prove to be an effective drug targets in the present scenario where the emergence of MDR and XDR tuberculosis has challenged the efficacy of current drug regime.
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