Effects of Nasopharyngeal Cancer's Patients Irradiation in Thyroid Function

Out of 80 nasopharyngeal carcinoma patients, who were received a radical radiation dose in the range of 6000 6500 cGy at radiation and isotopes center of Khartoum RICK and planned for conventional radiotherapy, as assessment for thyroid hormones level T4, T3 and TSH have been studied after receiving an average dose of 2036 702 cGy. Accordingly the analysis of the data showed that the thyroid hormones (T4 and T3) decreases as a results of irradiation and the reduction persists following radiation dose in a linear form by a factor of 0.02 nmol/l/cGy and 0.0004 nmol/cGy respectively while the TSH increases following the radiation dose increment and the increment factor was 0.0006 umol/cGy.