Dyslipidemia as Early Indicator of Diabetic Triopathy

Background Diabetes is fast gaining the status of a potential epidemic in India with more than 62 million diabetic individuals currently diagnosed with the disease1, 2. It is predicted that by 2O3O DM may afflict up to 79.4 million individuals in India3, 4, Few studies have assessed the relative associations of lipid fractions with diabetic microvascular events. Our aim was to determine a correlation between serum lipid profile and microvascular complication of DM patients. Material and methods This retrospective study was done among 141T1DM and 119T2DM patients attending or enrolled in Medicine or Geriatric OPD or indoor patients at SP MC Bikaner Rajasthan from june2009 to Dec 2011. Statistical program SPSS 10, student t test and chi square test were employed for assessment of data. Results There was statistically significant correlation between total cholesterol, LDL, VLDL and triglyceride with microvascular complications (pless than.001). Low level of HDL cholesterol were highly significant in retinopathy and neuropathy (pless than.001). while significant association was observed with nephropathy (pless than.01). Conclusion All microvascular complications were more with early onset and long duration of diabetes. Retinopathy was more in male as compared to females in T1DM patients, whereas neuropathy was more in female as compared to male in T2DM patients. Hence regular monitoring of lipid profile and screening for microvascular complication should be followed.