Mercury Toxicity in Hormonal Effects to Fresh Water Fish Cirrhinus Mrigala

Mercury interfere with a number of processes, regulated by the thyroid hormones T3 and T4 including blood vessel dilation, neurotransmission and immune function. Mercury chloride exposure toxic to the kidney, stomach, and intestines and lead increased blood pressure. Mercury chloride is the chemical compound of mercury and chlorine with the formula HgCl2. Mercuric salts generally target the gastrointestinal tract extensive precipitation of enterocytes protein occurs, with abdominal pain, vomiting and bleed diarrhea with potential necrosis of the gut mucosa. This may produce death either from peritonitis or from septic hypovolemic shock. Surviving patients commonly develop renal tubular necrosis with anuria. Brain dysfunction also occurs due to exposure of mercury. Plasma triiodothyronine (T3) of fish Cirrhinus mrigala exposed to sub lethal concentrations of mercury was presented in Table 2. The plasma triiodothyronine (T3) levels was decreased as the exposure period extended showing a percent decrease of -46.66, -53.84, -10.00, -64.28, -66.66 at the end of 7th, 14th, 21th, 28th, and 35th day, respectively. Table 3 gives data on change in the plasma thyroxin (T4) level of fish Cirrhinus mrigala exposed to sub lethal concentration of mercury. T4 level was also decreased throughout the treatment period showing a percent decrease of -72.29, -73.10, -76.02, -79.86, -79.02 at the end of 7th, 14th, 21st, 28th, and 35th, days respectively.