Histocytological Correlation Study of Thyroid Gland Lesions

BACKGROUND There is some grey zone In thyroid cytology where the diagnostic efficacy declines sharply rendering it difficult to categorize the lesions results in discrepancy. OBJECTIVE The aim of the present study is to determine the sensitivity, specificity, and accuracy of FNAC in the diagnosis of thyroid lesions and to correlate cytological findings with histopathology. MATERIAL AND MATHOD A Prospective study of FNAC of thyroid lesions was carried out along with its histopathological correlation starting from 1st October 2013 to 30th September 2015 at the P. D. U. Medical College and Hospital, Rajkot, Gujarat (India). Out of 886 thyroid lesions aspirated in cytology, we studied 80 cases followed by histopathplogical examination. Results The sensitivity, the specificity, accuracy, false positive rate, false negative rate of FNAC for the diagnosis of solitary thyroid nodules were 92.85 %, 98.48 %, 97.5 %, 1.56 %, 7.14 %. Conclusion The fine needle aspiration cytology is a simple, safe, cost effective, time saving, and minimally invasive procedure with a high diagnostic yield accuracy, sensitivity and specificity.