Pancytopenia a Three Years Evaluation

BACK GROUND Pancytopenia is an important clinico-hematological entity encountered in our day to day practice from a number of disease processes primarily and secondarily involving bone marrow (1, 2). The severity of pancytopenia and the underlying pathology determine the management and prognosis of the patients (3). The present study has been undertaken to evaluate the various causes and to correlate the peripheral blood findings with bone marrow aspirate which helps in the treatment (4). The objective is to study pancytopenia due to various causes and to evaluate hematological parameters. Methodology is retrospective study of 106 cases of pancytopenia on clinical and hematological parameters was done in the department of pathology, RIMS Medical college kadapa, AP, India during November 2011 to October 2014. The result of 106 cases showed the commonest physical finding was pallor and megaloblastic anaemia was the predominent hematological picture. Bone marrow evaluation is conclusive in all cases. The present study concludes that detailed primary hematological investigations along with bone marrow evaluation are helpful for the understanding of the disease process and to diagnose or to rule out the causes of pancytopenia and to plan for further investigations and management.