A Study Paper : Novel Approaches for Invasive and Non-Invasive Vagus Nerve Stimulation

The vagus nerve stimulation non-invasively is an approved therapy for the treatment of adult patients and adolescents and which is used to treat few neurological disorders such as epilepsy, major depressive disorder, schizophrenia, depression etc. The vagus nerve is 10th cranial nerve (longest nerve) connected to major parts of body. The electrical stimulation from vagus nerve stimulator/generator is passed through electrodes/leads placed around vagus nerve near neck to decrease high excitation of brain which is caused due to imbalance in electrical and chemical activity in brain. The stimulator consists of microcontroller/programmer used for controlling timing and intensity of electrical pulses provided to brain to avoid seizers. The decrease/control in excitation of brain reduces possibilities of seizer attacks in patients to avoid patients from facing hazardous effects due to continuous/abnormal seizers. Hence this study is to compare efficacy and reliability of devices used as vagus nerve stimulator.